细菌外层的细胞壁起着维持菌形及保护菌体内部结构的作用.由于抗生素、溶菌酶、抗体、补体及溶葡萄球菌素等各种体内外因素的影响,可以造成细菌细胞壁的损伤或缺失.这类细胞壁缺陷菌,称为细菌的L型.由于操作技术的改进,已可从各种临床标本中分离出细菌的L型;尤以泌尿系统感染中报导较多,对L型菌在人及实验动物的慢性肾盂肾炎中的意义也有所了解,本文就这一方面加以综述. Bacterial outer cell wall plays the role of maintaining the bacterial shape and protecting the internal structure of the bacterial cell.Because of various in vitro and in vivo factors such as antibiotics, lysozyme, antibody, complement and lysostaphin, the damage or deletion of the bacterial cell wall can be caused Such cell wall defect bacteria, known as the bacterial L type .Because of the improvement of operational techniques, has been isolated from a variety of clinical specimens of L-type bacteria; especially urinary tract infections reported more on the L-type bacteria in The significance of chronic pyelonephritis in humans and laboratory animals is also well understood and reviewed in this article.