目的　改进兔VX2肝癌模型的制作使之更适合介入治疗学研究 ,同时探讨瘤灶的CT表现及螺旋CT在检测瘤灶中的作用。材料与方法　实验动物为新西兰大白兔 (80只 ) ,瘤种采用动物自身接种传代保存。取瘤块组织 (1～ 2mm3 大小 )接种肝脏左叶深部 ,于接种后 7、14天分别行CT平扫、动脉早期、门脉期扫描 ,少数动物于接种后 2 1天再次CT扫描。结果　 72只 (90 % )动物接种成功。瘤灶以种植后 2周CT显示最清楚和典型 ,直径 1～ 2cm左右 ,平扫呈低密度或等密度 ,动脉早期明显强化 ,门脉期呈低密度 ,与周围肝组织分界较清楚。肝动脉造影显示肿瘤富血供。而种植后超过 3周的肿瘤大部分发生坏死 Objective To improve the production of rabbit VX2 hepatocarcinoma model to make it more suitable for interventional therapy research. At the same time, the CT appearance of tumor foci and the role of spiral CT in the detection of tumor foci were explored. Materials and Methods The experimental animals were New Zealand white rabbits (80 animals). The tumor species were inoculated with animals for passage and preservation. A tumor mass (1 to 2 mm3 in size) was inoculated into the deep left lobe of the liver. On the 7th and 14th day after inoculation, CT scans, early arterial and portal phase scans were performed, and a few animals were scanned again on day 21 after inoculation. Results 72 (90%) animals were successfully inoculated. The tumors were most clearly and typically shown on CT at 2 weeks after implantation, with a diameter of 1 to 2 cm. The plain scan showed low density or isodensity. The early arterial enhancement was obvious. The portal vein showed low density, and the boundary with the surrounding liver tissue was clear. Hepatic arteriography showed a rich blood supply to the tumor. Most of the tumors that have been implanted for more than 3 weeks have necrosis