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目的分析对肺癌伴恶性胸腔积液患者进行手术切除原发病灶以及手术后的联合治疗所取得的疗效。方法将50例肺癌伴恶性胸腔积液患者随机分成治疗组和对照组各25例。治疗组采用B超进行准确定位,同时将中心静脉导管置入到下行胸腔内,接上引流袋,实现恶性胸腔积液的引流,然后再次对胸部进行B超复查,若仍提示有积水,则使用顺铂(60-90mg)加高聚生金葡素(16-20ml)加生理盐水(40ml)对患者进行胸腔灌注后夹管,每周注射1次,连用3周。对照组患者采用与治疗组相同的方法,但在进行胸腔灌注药物时,采用同剂量(60-90mg)顺铂加生理盐水(20-40ml)注入。结果治疗组总有效率为88.0%,对照组总有效率为72.0%,两组比较存在显著差异(P<0.05)。结论肺癌伴恶性胸腔积液属于常见病和高发病,发病率及死亡率都比较高。在治疗中采用联合注入顺铂加金葡素的疗效明显高于单纯注入顺铂的疗效,患者应采用合适的治疗方式及时治疗,以免延误病情,发生生命危险。
Objective To analyze the curative effect of primary resection of primary lung cancer patients with malignant pleural effusion and postoperative combined treatment. Methods Fifty patients with malignant pleural effusion of lung cancer were randomly divided into treatment group (n = 25) and control group (n = 25). The treatment group using B-to accurately locate the same time, the central venous catheter into the descending thoracic cavity, connected to the drainage bag, to achieve drainage of malignant pleural effusion, and then once again on the chest B-ultrasound, if still prompted to have water, Patients were then thoracic perfusion with cisplatin (60-90 mg) plus hypercoagulation of gluconeo (16-20 ml) plus saline (40 ml) piped once per week for 3 weeks. Patients in the control group were treated in the same manner as the treatment group but with the same dose (60-90 mg) of cisplatin plus saline (20-40 ml) during the thoracic perfusion. Results The total effective rate was 88.0% in the treatment group and 72.0% in the control group. There was significant difference between the two groups (P <0.05). Conclusions Lung cancer with malignant pleural effusion is a common disease and a high incidence of morbidity and mortality are relatively high. In the treatment of joint injection of cisplatin plus kainicin efficacy was significantly higher than the simple injection of cisplatin efficacy, patients should be treated with appropriate treatment in a timely manner, so as not to delay the disease, life-threatening.