原发性血小板减少性紫癜(ITP)是小儿常见的出血性疾病,近年来的免疫学研究提示其发病与免疫作用有关。既往应用肾上腺皮质激素治疗以口服强的松为主,时间长,疗效差,且副作用大。我们自1990年2月起应用大剂量地塞米松冲击治疗21例ITP患儿,获得满意效果,分析如下:1临床资料1.1诊断标准:根据全国小儿血液病专题座 Primary thrombocytopenic purpura (ITP) is a common hemorrhagic disease in children, recent immunological studies suggest that its pathogenesis and immune function. Previous application of adrenal corticosteroids prednisone predominate, a long time, poor efficacy, and side effects. We since February 1990 since the application of high-dose dexamethasone shock treatment of 21 cases of ITP children with satisfactory results, the analysis is as follows: 1 Clinical data 1.1 diagnostic criteria: According to the National Pediatric Hematology Symposium