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目的：前瞻性研究米索前列醇（Ｍｉｓｏ）、低位水囊（ＬＰＷＢ）及小剂量催产素（ＯＸ）静脉滴注３种引产方法的有效性及对母、婴的影响。方法：将１２４例单胎、头位、、宫颈Ｂｉｓｈｏｐ评分＜５分、足月妊娠初产妇随机分为３组：Ｍｉｓｏ组４１例，ＬＰＷＢ组４３例，ＯＸ组４０例；３种方法引产后，如宫颈Ｂｉｓｈｏｐ评分≥７分，则行人工破膜术。结果：ＬＰＷＢ组及Ｍｉｓｏ组较ＯＸ组、宫颈Bｉｓｈｏｐ评分＜５分显著提高（Ｐ＜０．００１，P＜０．０１），引产到临产时间明显缩短（Ｐ＜０．００１，Ｐ＜０．０５），但３组间母、婴并发症差异无显著性。结论：对宫颈不成熟孕妇采用ＬＰＷＢ及Ｍｉｓｏ引产安全、有效、经济，可靠，ＯＸ静脉滴注引产不宜作为首选引产方法
OBJECTIVE: To prospectively study the efficacy and adverse effects of three kinds of induction of misoprostol (Misoprostol, low water balloon (LPWB) and low-dose oxytocin (OX)) on mother and infant. Methods: 124 cases of single-fetus, head-head and cervical Bishop score <5 were randomly divided into three groups: 41 in Miso group, 43 in LPWB group and 40 in OX group. The three methods , Such as cervical Bishop score ≥ 7 points, the line of artificial rupture. Results: Compared with OX group and cervical smear group, the Bishop score of LPWB group and Miso group increased significantly (P <0.001, P <0.01) and the time of induction of labor to labor was significantly shorter (P <0.001, P <0. 05), but there was no significant difference between the three groups in the complication of maternal and infant. Conclusion: It is safe, effective, economical and reliable for LPJB and Miso induced labor in immature cervical pregnant women. Oxygen inoculation by OX should not be used as the preferred method of induction of labor