论文部分内容阅读
在机械通气的病人中,医源性下呼吸道感染是一个重要问题。而G~-杆菌常存在于患者的口咽部,增加了这种感染的可能性。作者对收入呼吸监护室的病人联合应用预防性抗生素,以期使口咽部达到无G~-杆菌状态,并减少其向下呼吸道移生和感染。 27例病人,均患有严重的内外科疾病,需要长期的呼吸监护。所有患者均通过气管插管或气管切开接受机械通气10天以上。监护期间的医疗护理严格遵守无菌操作原则。病人收入ICU后即行口咽部和气管内吸出物的细菌培养,作为对照;以后每周两次追踪细菌培养。首次细菌培养之后,即每日经静脉给予Cefotaxime50～100 mg/kg,持续至口咽部细菌培养阴性后停药;
In patients with mechanical ventilation, iatrogenic lower respiratory tract infection is an important issue. While G ~ - bacteria often exist in the oropharynx of patients, increasing the possibility of this infection. The authors co-administered prophylactic antibiotics to patients admitted to the Respiratory Care Unit with a view to achieving a non-G-bacilli status in the oropharynx and reducing their down-going respiratory transplants and infections. Twenty-seven patients, both with serious internal and external medical conditions, required long-term respiratory monitoring. All patients received mechanical ventilation for more than 10 days by endotracheal or tracheostomy. Medical care during custody strictly follows the principle of aseptic technique. Bacterial culture of the oropharyngeal and endotracheal aspirates was performed after the patient’s income from the ICU as a control; bacterial cultures were followed twice weekly thereafter. After the first bacterial culture, Cefotaxime 50 ~ 100 mg / kg was intravenously administered daily until the bacteria in the oropharynx became negative and then stopped.