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作者根据现场研究资料和理论统计论述了轮状病毒和霍乱免疫对幼儿腹泻发病率和死亡率的可能影响.要使轮状病毒和霍乱免疫成为控制腹泻的有效措施,必须使下列三种假设成为现实:(1)由轮状病毒(RV)或01群霍乱弧菌(VC01)引起的幼儿腹泻发病率和死亡率相当高;(2)抗RV、VC01或其产物的疫苗具有降低由这些病原引起的腹泻发病率、死亡率或严重性的能力;(3)轮状病毒或霍乱免疫(当已有有效疫苗时)具有降低幼儿腹泻总发病率、死亡率或减轻腹泻症状的能力.
Based on field research data and theoretical statistics, the authors discuss the possible impact of rotavirus and cholera immunization on morbidity and mortality of children with diarrhea. To make rotavirus and cholera immunization an effective measure to control diarrhea, the following three assumptions must be made Reality: (1) The incidence and mortality of childhood diarrhea caused by rotavirus (RV) or Vibrio cholerae 01 group 01 (01) are quite high; (2) vaccines against RV, VC01 or their products have a decreased risk of developing diarrhea caused by these pathogens (3) The ability of rotavirus or cholera immunization (when a valid vaccine is available) to reduce the overall incidence of diarrhea, mortality or the diarrheal symptoms in young children.