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目的了解克拉玛依市健康人群乙型肝炎(乙肝)抗体水平,为防控乙肝提供参考依据。方法按照随机抽样方法,采集0~60岁健康人群1 056人份血样,应用酶联免疫吸附试验(ELISA)法定量检测乙肝表面抗体(抗-HBs)、乙肝核心抗体(抗-HBc);定性检测乙肝表面抗原(HBs Ag)。结果检测1 056人,人群HBs Ag阳性率为1.99%,抗-HBc阳性率为14.30%,抗-HBs阳性率为79.17%,抗-HBs几何平均浓度(GMC)为159.90 m U/ml;乙肝病毒(HBV)感染率为14.49%。15岁以下儿童HBs Ag阳性率为0.16%,抗-HBs平均阳性率为80.65%,HBV感染率为3.27%。结论该市人群乙肝流行特征发生改变,15岁以下儿童HBs Ag阳性率、HBV感染率下降明显。25岁以上成人感染率高,今后应加大成人乙肝防治的宣传,提高人群乙肝疫苗接种率。
Objective To understand the level of hepatitis B (HBeAg) antibodies in healthy people in Karamay City and provide a reference for prevention and control of hepatitis B. Methods A total of 1 056 blood samples were collected from healthy population aged 0-60 years according to the random sampling method. Serum anti-HBs and anti-HBc were detected by enzyme linked immunosorbent assay (ELISA) Detection of hepatitis B surface antigen (HBsAg). Results The positive rate of anti-HBsAg was 1.99%, anti-HBc positive rate was 14.30%, anti-HBs positive rate was 79.17%, anti-HBs geometric mean concentration (GMC) was 159.90 mU / ml. Virus (HBV) infection rate was 14.49%. The positive rate of HBs Ag in children under 15 years old was 0.16%, the average positive rate of anti-HBs was 80.65%, and the infection rate of HBV was 3.27%. Conclusion The epidemiological characteristics of hepatitis B in the population of the city changed. The positive rate of HBsAg and HBV infection in children under 15 years old decreased significantly. Adults over 25 years old infection rate is high, should increase the publicity of prevention and treatment of adult hepatitis B in the future, raise population hepatitis B vaccination rate.