鉴于钙拮抗剂可以松弛血管平滑肌,缓解动脉痉挛,已在儿科领域里广泛应用。作者最近以钙拮抗剂硝苯吡啶治疗小儿雷诺病,获得满意疗效。3例患原发性雷诺病的女孩(年龄10、13、13.5岁各1例),均具有手指疼痛、发冷及遇冷后局部皮肤苍白、发绀等症状。实验室检查正常,未发现胶原 In view of calcium antagonists can relax vascular smooth muscle, relieve arterial spasm, has been widely used in pediatric fields. The author of calcium antagonist nifedipine recently treated children with Raynaud’s disease, access to satisfactory results. Three patients with primary Raynaud’s disease (age 10, 13 and 13.5 years old each) had symptoms of finger pain, chills, and pale skin and cyanosis after cooling. Laboratory tests were normal, no collagen was found