论文部分内容阅读
自1949年paueing发现镰刀状贫血病人RBC含有HbS以来,引起了遗传学、临床医学及生物化学家的广泛研究兴趣,从而阐明了异常Hb(包括Hb变种及地中海贫血病等)是由于基因的突变或缺失等引起的。迄今已发现的Hb约有360余种,其中多数变种对人类是无害的,但有少数则可影响人的身体健康,甚而危及生命,有关Hb变种在我国的地理分布、人群中的发生率以及变种的鉴定等方面报导资料颇多。我省边疆地区是多种少数民族聚居地之一,历史上为恶性疟疾流行区域,因而调查其异常Hb的地理分布,在人群
Since 1949, Paueing discovered that HibS in RBCs of sickle-shaped anemia patients have attracted a great deal of interest from genetics, clinical medicine and biochemists, thus clarifying that abnormal Hb (including Hb variants and thalassemia, etc.) are due to gene mutations Or missing caused. Hb has been found so far about 360 species, most of which are harmless to humans, but a few can affect people’s health, and even life-threatening, the geographical distribution of Hb variants in our country, the incidence of the crowd As well as the identification of variants reported a lot of information. The frontier region of our province is one of a large number of ethnic minority settlements, historically a region of endemic malaria, and thus investigate the geographical distribution of abnormal Hb in the population