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自1982年Burrows等[1]首先报告在结直肠癌围手术期(简称围术期)中,接受输异体血患者5年生存率明显低于未输血患者以来,国内外许多研究证实输血除了替代性治疗及恢复患者生理功能治疗作用外,可能增加术后感染、肿瘤复发、器官功能衰竭等并发症的发生。至目前为止,大部分国外学者认为围术期输血可导致肿瘤发生免疫逃逸诱发转移,
Since 1982, Burrows et al [1] first reported in the perioperative period of colorectal cancer (perioperative period), 5-year survival rate of patients receiving transfusion of blood was significantly lower than that of patients without blood transfusions, many studies have confirmed that blood transfusion in addition to replacement Sexual treatment and recovery of patients with physiological function of the therapeutic effect, may increase postoperative infection, tumor recurrence, organ failure and other complications. So far, most foreign scholars believe that perioperative blood transfusion can cause immune escape induced tumor metastasis,