【摘 要】
：
Natural products serve as abundant resources with diversity of chemical structures, which has been widely explored for the pharmacological researches and drug discovery [1, 2].They are generally isolated from microorganisms,plants, marine organisms, etc.,
【机 构】
：
State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences,
论文部分内容阅读
Natural products serve as abundant resources with diversity of chemical structures, which has been widely explored for the pharmacological researches and drug discovery [1, 2].They are generally isolated from microorganisms,plants, marine organisms, etc., with multifarious pharmacological activities [3].To date, natural products and their derivatives have been extensively used for the treatment of various diseases, such as malarial, immune-related diseases and cancer [4-7].According to a statistical data from 1946 to September 2019, there are 13.5％ and 25.1％ of approved anti-cancer drugs originating from natural products and natural product derivatives, respectively [1], indicating the essential role of natural products in anti-cancer drug development.
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