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目的：探讨丹参多酚酸盐联合阿斯匹林治疗急性脑梗死的临床疗效。方法将219例急性脑梗死患者按照完全随机原则分为两组,均给予吸氧、控制血压及改善脑循环等急性脑梗死常规治疗,观察组在此基础上给予丹参多酚酸盐联合阿斯匹林治疗,观察4周。治疗前后采用脑卒中病人神经功能缺损程度评分标准评定神经功能缺损程度及临床疗效,同时检测血清 C反应蛋白水平的变化。结果治疗4周末两组神经功能缺损程度评分及血清 C 反应蛋白水平均较治疗前显著降低(P <0.01),但观察组较对照组下降更显著(P <0.01)。观察总有效率(91.0%)显著高于对照组(76.9%,P <0.01)。结论急性脑梗死患者在常规治疗的基础上予以丹参多酚酸盐联合阿斯匹林治疗具有协同增效作用,能显著改善患者的神经功能缺损状况,更有利于患者的临床康复。“,”Objective To explore the efficacy of salvianolate combined with aspirin in the treatment of a-cute cerebral infarction (ACI).Methods A total of 21 9 ACI patients were assigned to two groups accord-ing to completely randomized principle,both groups received acute cerebral infarction routine treatment of oxygen inhalation,controlling blood pressure and improving cerebral circulation and so on,on this basis observation was plus salvianolate and aspirin for 4 weeks.Neurologic impairments and efficacies were as-sessed with the Scandinavian Stroke Scale (SSS)and changes of C-reactive protein (CRP)levels detected at the same time.Results At the end of the 4 th week treatment neurologic impairment scores and CRP levels of both groups lowered more significantly compared with pretreatment (P <0.01),so did those in observation than in control group (P <0.01).The total effective rate was significantly higher in observa-tion than in control group (91/0% vs.76.9%,P <0.01).Conclusion Salvianolate combined with aspi-rin on the basis of routine treatment has a synergism in the treatment of acute cerebral infarction,could notably improve patients’neurologic impairment,and is more beneficial to patients’clinical rehabilitation.