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为给临床有效控制耐苯唑青霉素金黄色葡萄球菌（MRSA）感染提供依据，对临床分离的141株金黄葡萄球菌进行β-内酰胺酶测定及药敏分析.结果：临床分离菌的60.1％为MRSA.成人组MRSA为680％，儿童组MRSA为52.3％.总体菌株中产β-内酰胺酶株为63.8％，MRSA产β-内酰胺酶株为776％，苯唑青霉素敏感金葡菌（MSSA）产β-内酸胺酶为42.3％.药敏分析显示：金葡菌对万古霉素无耐药菌株.对头孢哌酮、头孢唑啉、丁胺卡那霉素、氯霉素、庆大霉素、诺氟沙星、苯唑青霉素的耐药性分别为15.2％、16.3％、182％、21.0％、32.6％、39.7％、60.1％.
To provide a basis for effective clinical control of oxacillin-resistant Staphylococcus aureus (MRSA) infection, 141 Staphylococcus aureus isolates were assayed for β-lactamase and drug susceptibility.Results: 60.1% of clinical isolates were MRSA was 680% in adult group and 52.3% in MRSA group. The overall strain producing β-lactamase was 63.8%, MRSA producing β-lactamase was 776%, and the susceptibilities of oxacillin-susceptible Staphylococcus aureus (MSSA ) Produced β-lactamase enzyme was 42.3% .Analysis of drug susceptibility showed that: Staphylococcus aureus no vancomycin-resistant strains of cefoperazone, cefazolin, amikacin, chloramphenicol, Qing The antibacterials of gentamicin, norfloxacin and oxacillin were 15.2%, 16.3%, 182%, 21.0%, 32.6%, 39.7% and 60.1%, respectively.