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目的:比较薄层细胞学检测系统(Thinprep cytologic test,TCT)及传统的宫颈细胞巴氏涂片(conventionalsmears,CS)对高级别宫颈癌前病变的诊断价值。方法:将2007年1月～2011年9月在上海市松江区中心医院进行宫颈癌筛查的30 869例妇女分为TCT组和CS组,TCT组12 458例,CS组18 411例,比较两组的阳性率及病检符合率。结果:TCT组CINⅡ的病检符合率高于CS,有统计学意义;且CINⅡ+CINⅢ病检符合率明显高于CS组。结论:TCT用于早期发现宫颈癌前病变有优势,特别是对于CINⅡ及以上的高级别宫颈病变的早期发现较CS更准确,因此,TCT检查是宫颈癌早期筛查的首选方法。
Objective: To compare the diagnostic value of Thinprep cytologic test (TCT) and traditional cervical smears (CS) on cervical precancerous lesions of high grade. Methods: From January 2007 to September 2011, 30 869 women who underwent cervical cancer screening in Shanghai Songjiang Central Hospital were divided into TCT group and CS group, 12 458 in TCT group and 18 411 in CS group The two groups of positive rate and disease detection coincidence rate. Results: The coincidence rate of CINⅡ in TCT group was higher than that of CS, and the coincidence rate of CINⅡ + CINⅢ was significantly higher than that in CS group. CONCLUSION: TCT is an effective method for early detection of precancerous lesions of the cervix. In particular, early detection of high-grade cervical lesions of CIN II and above is more accurate than that of CS. Therefore, TCT is the first choice for early screening of cervical cancer.