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目的观察榄香烯注射液配合放疗治疗肺癌脑转移的临床效果。方法选取肺癌脑转移患者40例,随机分为观察组和对照组,每组20例。观察组采用榄香烯注射液配合放疗治疗,对照组单纯放疗治疗。观察比较2组治疗效果、不良反应及生存期。结果观察组总缓解率为50.0%,高于对照组的20.0%,差异有统计学意义(P<0.05);观察组不良反应发生率为50.0%,低于对照组的80.0%,差异有统计学意义(P<0.05);观察组1年内病死率为15%(3/20),低于对照组的50.0%(10/20),差异有统计学意义(P<0.05)。结论榄香烯注射液配合放疗治疗肺癌脑转移具有较好的疗效,且不良反应小,能有效延长患者的生存率,值得临床推广。
Objective To observe the clinical effect of elemene injection combined with radiotherapy in the treatment of brain metastases of lung cancer. Methods Forty patients with brain metastases from lung cancer were randomly divided into observation group and control group, with 20 cases in each group. The observation group was treated with elemene injection with radiotherapy, and the control group with radiotherapy alone. Two groups were observed and compared the treatment effect, adverse reactions and survival. Results The total remission rate in the observation group was 50.0%, which was higher than that in the control group (20.0%, P <0.05). The incidence of adverse reactions in the observation group was 50.0%, which was lower than 80.0% of the control group (P <0.05). The 1-year mortality rate in the observation group was 15% (3/20), which was lower than 50.0% (10/20) in the control group (P <0.05). Conclusion Elemene injection combined with radiotherapy for the treatment of brain metastases of lung cancer has a good curative effect, and the adverse reaction is small, which can effectively prolong the survival rate of patients and is worthy of clinical promotion.