转化生长因子-α(TGF-α)为膜强白上皮生长因子家族的一员,在包括肺等脏器的胚胎发展中具有重要作用。就急性肺损伤肺水肿液中是否存在具有生物意义浓度的 TGF-α,以及 TGF-α在急性肺损伤中意义进行了研究。文章作者检测了急性肺损伤住院患者的肺水肿液。样本3000g 离心后,以双缩脲方法测定肺水肿液,与血浆总蛋白水平。根据临床资料和肺水肿液与血浆 Transforming growth factor-alpha (TGF-alpha), a member of the membrane-derived epithelial growth factor family, plays an important role in the development of embryos, including lungs and other organs. The existence of biologically significant concentrations of TGF-α in acute lung injury pulmonary edema and the significance of TGF-α in acute lung injury were investigated. The authors examined pulmonary edema fluid in hospitalized patients with acute lung injury. After centrifugation at 3000 g of the sample, the pulmonary edema fluid and the total plasma protein level were measured by the biuret method. According to clinical data and pulmonary edema fluids and plasma