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本实验应用中药苍术作为耐药性（Ｒ）质粒消除剂，以痢疾杆菌Ｆ＿１３株为靶细菌进行Ｒ质粒的体外消除试验。其消除率对耐ＴＣ＋ＳＭ＋ＡＰ和耐ＳＭ分别为０．８％和４６％；对照组的ＥＢ消除率为０．８％，ＳＤＳ消除率为０．６％。对照组的消除子均表现为对单一耐药性的丢失。
In this experiment, Chinese herb Atractylodis rhizomae was used as a drug-resistance (R) plasmid elimination agent, and Shigella spp. F13 strain was used as target bacteria for in vitro elimination of R plasmid. The elimination rate was 0.8% and 46% for TC+SM+AP and SM, respectively. The EB elimination rate for the control group was 0.8% and the SDS elimination rate was 0.6%. Eliminations in the control group all showed loss of single resistance.