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目的：探讨健康成人和高血压病（ＥＨ）、冠心病（ＣＨＤ）患者心室肌复极功能的昼夜差异及其与心率变异性（ＨＲＶ）的关系。方法：随机选取健康成人３５例，ＥＨ、ＣＨＤ患者５６ 例。作２４ 小时动态心电图检查，计算机软件自动计算ＨＲＶ时域参数， 专人测量ＲＲ、ＱＴ间期。结果：两组对象夜间ＱＴ间期均显著长于白昼（Ｐ分别小于００５～０．０１）。患者ＱＴ间期均长于对照组，但仅以心率６０ ｂｐｍ～８０ ｂｐｍ 时患者ＱＴ间期显著长于对照组。ＱＴ间期与ＨＲＶ明显相关。结论：ＥＨ、ＣＨＤ患者ＨＲＶ和心室肌复极功能均受损
Objective: To investigate the diurnal variation of ventricular repolarization function in healthy adults and patients with essential hypertension (EH) and coronary heart disease (CHD) and its relationship with heart rate variability (HRV). Methods: 35 healthy adults were randomly selected, and 56 EH and CHD patients were selected. For 24-hour Holter examination, the computer software automatically calculates the HRV time domain parameters, hand-measured RR, QT interval. Results: The nighttime QT interval of both groups was significantly longer than that of daytime (P <005 ~ 0.01 respectively). Patients with QT interval were longer than the control group, but only in patients with heart rate 60 bpm ~ 80 bpm QT interval was significantly longer than the control group. QT interval was significantly associated with HRV. Conclusion: Both HRV and ventricular repolarization were impaired in EH and CHD patients