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慢性肾脏疾病(CKD)患者随着肾功能的恶化,其总体病死率和心血管疾病死亡风险显著升高. 处于不同分期病程的CKD患者,其血脂异常的质和量具有特殊性,影响临床终点事件. 他汀类药物具有减低胆固醇、预防心血管事件风险、保护肾功能等作用,不同他汀在不同分期 CKD患者中的疗效及安全性可能存在差异. 该文就不同分期CKD患者的治疗策略予以综述.“,”Patients at all stages of chronic kidney disease(CKD) have a significantly elevated risk of all-cause and cardiovascular mortality as renal function declines.The lipid profile shows various features both in qualitative and quantitative abnormalities in patients with CKD of different stages,which affects the clinical outcomes.The application of statins can lower the lipid level in patient , prevent cardiovascular events and protect renal function,although the curative effect and safety of different statins used in patients with CKD of different stages are various.Here is to make a review of different statin therapies for CKD of different stages .