患者男，１６岁，学生，因发热２８天入院，最高体温达 ３９． ５ ℃，伴乏力，纳差和头晕，予氨苄青霉素、红霉素等治疗７天，无明显好转，骨髓穿刺检查出利什曼原虫，诊断为黑热病，予葡萄糖酸锑钠治疗７天无效，转入我院。体检：慢性消耗病容，浅表淋巴结无肿大，心、肺正常 Male patient, 16 years old, student, admitted to hospital for 28 days due to fever, the maximum temperature of 39. 5 ℃, with fatigue, anorexia and dizziness, to ampicillin, erythromycin and other treatment for 7 days, no significant improvement in bone marrow biopsy Leishmania, diagnosis of kala-azar, anti-gluconate treatment of 7 days invalid, Into our hospital. Physical examination: Chronic consumption of disease, superficial lymph nodes without swelling, heart, lungs normal