随着重组人生长激素(rhGH)治疗适应证的不断增加,大大改善了矮身材儿童的身高和生活质量,同时GH治疗的相关不良反应越来越受到重视。成年GHD患者采用GH治疗会发生水肿、高血压及良性颅内高压,儿童采用GH治疗对水电解质平衡几乎没有影响,发生良性颅内高压的病例也相对较少,但会引发永久性的严重后遗症,需要定期随访。 With the increasing use of rhGH indications, the height and quality of life of short stature children have been greatly improved, and more and more attention has been paid to the adverse effects of GH treatment. GH treatment in adults with GHD causes edema, hypertension, and benign intracranial hypertension. Children treated with GH have almost no effect on the water-electrolyte balance and fewer cases of benign intracranial hypertension, but can cause permanent severe sequelae , Need regular follow-up.