据 Am J Health-Syst pharm 52:1199报道,由于生理和解剖的变异,患有糖尿病的病人出现下肢感染是很危险的,因此必须集中治疗并发症及感染复发。感染灶很可能存在几种病原菌,包括革兰阴性菌、革兰阳性需氧菌及厌氧菌。如果预防及非药物治疗不成功,那么开始系统抗生素治疗,经验治疗中最佳的抗生素选择是 According to Am J Health-Syst pharm 52: 1199, lower extremity infections in patients with diabetes are very dangerous due to physiological and anatomical variations, and complications and infection recurrence must be treated intensively. There are likely to be several pathogenic bacteria in the focus of infection, including gram-negative bacteria, gram-positive aerobic bacteria and anaerobic bacteria. If prophylaxis and nonpharmacologic treatment are unsuccessful, then systematic antibiotic treatment is initiated and the best choice of antibiotic in empirical therapy is