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目的:探讨以绝经状态,血清CA125和超声评分3者结合建立的恶性危险指数对附件包块术前诊断中的应用进行评价。方法:针对2001-01/2008-06附件包块患者475例,计算3种恶性危险指数判断恶性肿瘤的敏感度、特异度;统计图形用ROC曲线及ROC曲线下面积来评价诊断方法。结果:三种RM I的ROC曲线下面积均高于单一诊断指标,以200为临界值,RM I1,RM I2,RM I3的敏感度分别是57.1%、62.3%、59.0%。结论:恶性危险指数是诊断附件恶性肿瘤的良好指标,利于术前进行治疗方案的选定。
OBJECTIVE: To evaluate the application of premenopausal diagnosis in menopause, serum CA125 and ultrasonic score in combination with the establishment of malignant risk index. Methods: According to the 475 cases with mass in the annexe from January 2001 to June 2008, three malignant risk indexes were calculated to determine the sensitivity and specificity of the malignant tumor. Statistical analysis was performed using the ROC curve and the area under the ROC curve to evaluate the diagnostic method. Results: The area under the ROC curve of three kinds of RM I were all higher than the single diagnosis index, and the sensitivity of RM I1, RM I2 and RM I3 were respectively 57.1%, 62.3% and 59.0% with the threshold of 200. Conclusion: Malignant risk index is a good indicator of the diagnosis of malignant tumors of the attachment, which is conducive to the preoperative selection of treatment options.