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目的:探讨C-反应蛋白(CRP)与2型糖尿病合并脑血管意外的关系。方法:选取2型糖尿病合并脑血管意外患者53例作为研究对象。同时选取同期在汕头市潮阳区大峰医院住院的没有合并脑血管意外的2型糖尿病组53例,以及同时期在我院进行健康体检的55人作为对照组。分析比较3组患者C-反应蛋白的水平。结果:3组的血清超敏C-反应蛋白的比较结果显示,脑血管意外组的超敏C反应蛋白(hs-CRP)水平,显著高于非脑血管组,而两组的hs-CRP水平均显著高于对照组,差异均具有统计学意义(P<0.05)。合并脑血管意外组53例,根据患者的hs-CRP水平是否正常分为正常组(n=13)和异常组(n=40),hs-异常组中,死亡7例,致残13例,致残(死)率为50%(20/40)。hs-CRP正常组中,致残2例,致残率为15.38%(2/13)。组间比较,差异有统计学意义(P<0.05)。结论:C-反应蛋白与2型糖尿病合并脑血管意外具有显著相关性,对早期防治糖尿病脑血管意外病变有重要价值。
Objective: To investigate the relationship between C-reactive protein (CRP) and type 2 diabetes complicated with cerebrovascular accident. Methods: 53 type 2 diabetic patients with cerebrovascular accident were selected as the research object. Meanwhile, 53 patients with type 2 diabetes mellitus who did not have cerebrovascular accident who were hospitalized in Dayafeng Hospital, Chaoyang District, Shantou City during the same period, and 55 healthy people in our hospital during the same period were selected as the control group. Analysis and comparison of C-reactive protein levels in three groups. Results: The results of serum hs-CRP levels in three groups showed that the levels of hs-CRP in cerebrovascular accident group were significantly higher than those in non-cerebrovascular group, while the levels of hs-CRP Were significantly higher than the control group, the difference was statistically significant (P <0.05). Fifty-three patients with cerebrovascular accident complicated by cerebrovascular accident were divided into normal group (n = 13) and abnormal group (n = 40) according to whether hs-CRP level was normal or not. Among hs- Disability (death) rate was 50% (20/40). In the normal group of hs-CRP, 2 cases were disabled and the morbidity was 15.38% (2/13). The differences between the two groups were statistically significant (P <0.05). Conclusion: There is a significant correlation between C-reactive protein and type 2 diabetes mellitus with cerebrovascular accident, which is of great value in the prevention and treatment of diabetic cerebrovascular accident.