0　引言　尼群地平系钙离子拮抗剂 ,因其具扩张血管、降低血管阻力作用 ,临床已作为降门脉压力药物用于肝炎肝硬化门脉高压症的治疗 ,1997年我科用尼群地平治疗 32例患者 ,发生上消化道出血 4例 ,现报告如下 .1　对象和方法1.1　对象　 4例患者为男性 ,年龄 2 5～ 5 6岁 ,经血 0 Introduction nitrendipine calcium antagonists, because of its expansion of blood vessels, reducing vascular resistance, clinically as a portal hypertension drug used in the treatment of liver cirrhosis and portal hypertension in 1997, I use nitrendipine Treatment of 32 patients, the occurrence of upper gastrointestinal bleeding in 4 cases are reported as follows.1 objects and methods 1.1 object 4 patients were male, aged 25 to 56 years old, menstrual blood