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目的 探讨进展期胃肠道癌手术切除后腹腔复发转移的防治方法。方法 对 5 3例进展期胃肠道癌病人分组行围手术期持续腹腔温热化疗 ,并对其化疗术后 1、2、3年生存率对照研究。结果 2 7例病人实施腹腔化疗后 1、2、3年生存期分别为 88 46 % ,80 76 % ,6 9 2 3 %明显高于对照组的 84 6 1% ,6 1 5 %及 46 2 % ,且并发症与副作用无差异。结论 腹腔温热化疗对进展期胃肠道癌术后复发有良好的防治作用。
Objective To investigate the prevention and treatment of intraperitoneal recurrence and metastasis after surgical resection of advanced gastrointestinal cancer. Methods 53 consecutive patients with advanced gastrointestinal cancer underwent peritoneal thermochemotherapy by peritoneal thermotherapy and compared their 1, 2, 3 year survival rates after chemotherapy. Results The survival rates at 1, 2 and 3 years after celiac chemotherapy in 27 patients were 88 46%, 80 76% and 69 2 3%, respectively, which were significantly higher than 84 6 1%, 61 5% and 46 2 in the control group %, And no difference between complications and side effects. Conclusion Intraperitoneal hyperthermic chemotherapy has a good preventive and therapeutic effect on postoperative recurrence of advanced gastrointestinal cancer.