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为探讨肝母细胞瘤各组织类型的免疫表达和预后的关系，作者对２０例肝母细胞瘤进行了临床病理分析，其中１８例还作了７种标记的免疫组化染色。结果细胞角蛋白、甲胎蛋白、Ｓ－１００蛋白和波形蛋白在肿瘤上皮细胞浆的表达分别为１４例、１０例、９例和４例；细胞核中癌胚抗原、Ｐ５３和Ｐ１６蛋白的表达分别是１１例、９例和７例。此外，还有１例肿瘤的间叶成分同时出现Ｐ１６蛋白、波形蛋白、细胞角蛋白表达。由此提示不同组织学类型的肝母细胞瘤的免疫表达各异，并与肿瘤的分化和预后有关。
In order to investigate the relationship between the immunological expression and prognosis of hepatoblastoma tissue types, the authors performed a clinicopathological analysis of 20 hepatoblastomas, and 18 of them also performed immunohistochemical staining with 7 markers. Results The expressions of cytokeratin, alpha-fetoprotein, S-100 protein and vimentin in tumor epithelial cytoplasm were 14 cases, 10 cases, 9 cases and 4 cases respectively; the expressions of carcinoembryonic antigen, P53 and P16 protein in nucleus were respectively It was 11 cases, 9 cases and 7 cases. In addition, there is also a case of the tumor of the mesenchymal components of P16 protein, vimentin, cytokeratin expression. This suggests that different histological types of hepatoblastoma have different immune expression and are associated with tumor differentiation and prognosis.