论文部分内容阅读
目的报告1例罕见的多部位受累的上皮样肉瘤。方法回顾性分析患者的临床及病理资料、治疗及随访,并复习相关文献。结果患者男,47岁,先后发现腰部、颏下、耳前、头皮多部位肿块达十余个,组织病理检查示肿瘤由上皮样细胞和梭形细胞构成肉芽肿样结构,位于真皮胶原束之间,中央大片状坏死,肿瘤细胞轻-中度异型性。免疫组化显示细胞角蛋白(AE1/AE3)、上皮细胞膜抗原(EMA)和波形蛋白(vimentin,VIM)阳性,S-100和CD34灶状阳性。结论上皮样肉瘤是临床少见的软组织低度恶性肿瘤,多发性者罕见,容易误诊为良性肉芽肿性病变或其他恶性肿瘤,应引起临床及病理医师的足够重视。
Aim To report a rare case of multiple epithelial sarcoma involving multiple sites. Methods Retrospective analysis of clinical and pathological data, treatment and follow-up, and review the relevant literature. Results Male, 47 years old, had found more than ten lumps in the lumbar, submental, ear and scalp. Histopathological examination showed that the tumor consisted of granuloma-like structure of epithelial-like cells and spindle cells, located in dermal collagen bundles Between the large central necrosis, tumor cells light - moderate atypia. Immunohistochemistry showed cytokeratin (AE1 / AE3), epithelial membrane antigen (EMA) and vimentin (VIM) positive, S-100 and CD34-positive. Conclusions Epithelioid sarcoma is a rare clinical low grade soft tissue tumor with multiple rare and easily misdiagnosed as benign granulomatous or other malignant tumors and should attract enough attention of clinicians and pathologists.