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目的观察中西医结合治疗新生儿胆汁淤积症的临床疗效。方法将我院新生儿科收治的62例新生儿胆汁淤积症患儿随机分为治疗组32例和对照组30例,对照组给予口服苯巴比妥加蓝光照射治疗,治疗组在对照组治疗方法的基础上配合中药灌肠治疗,治疗7 d后比较2组患儿的临床疗效。结果对照组总有效率为63.3%,治疗组为87.5%,2组比较差异有统计意义(P<0.05);治疗7 d后2组血清总胆红素(TBIL),直接胆红素(DBIL)和胆汁酸(TBA)均较治疗前降低,差异均有统计意义(P<0.05),且治疗组TBIL,DBIL和TBA值下降幅度大于对照组,差异均有统计意义(P<0.05)。结论中西医结合治疗新生儿胆汁淤积症疗效显著,值得临床推广应用。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of neonatal cholestasis. Methods 62 cases of neonatal cholestasis admitted to neonatal department of our hospital were randomly divided into treatment group (32 cases) and control group (30 cases). The control group was given oral phenobarbital plus blue light irradiation. The treatment group in the control group Based on the traditional Chinese medicine enema treatment, the treatment of 7 d after the comparison of the clinical efficacy of two groups of children. Results The total effective rate of the control group was 63.3%, the treatment group was 87.5%, the difference between the two groups was statistically significant (P <0.05); after 7 days of treatment, the levels of total serum bilirubin (TBIL), direct bilirubin ) And bile acid (TBA) were lower than those before treatment (P <0.05), and the decrease of TBIL, DBIL and TBA in the treatment group was greater than that in the control group (P <0.05). Conclusion Integrative treatment of neonatal cholestasis significant effect, it is worthy of clinical application.