现代医学日益发展,广谱抗生素、免疫制剂及肿瘤放化疗等的广泛应用延长并改善了许多重症患者的生命,但同时也使得真菌感染日渐增多,特别是在免疫抑制疾病、恶性血液系统疾病、干细胞移植和器官移植中。念珠菌是侵袭性真菌病的主要病原体。据报道,在美国,念珠菌是引起院内血源性 The rapid development of modern medicine, broad-spectrum antibiotics, immunological agents and radiotherapy and chemotherapy and other widely used to extend and improve the lives of many critically ill patients, but also make increasing fungal infections, especially in immunosuppressive diseases, hematologic malignancies, Stem cell transplantation and organ transplantation. Candida is the major causative agent of invasive fungal diseases. It is reported that in the United States, Candida is caused by hospital blood