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目的观察中医药二联疗法对成人大骨节病的临床疗效,选出质优、价廉、疗效好和副作用小的治疗方法。方法选择确诊的成人大骨节病患者69例,随机分成中医药二联疗法治疗组34例和西医组35例,中医药二联疗法治疗组给予自拟内服汤药制剂和离子导入治疗,西医组给予口服硫酸软骨素和维生素E。结果治疗前后西医组(t=9.418)和中医组(t=7.662)的临床疗效差异有统计学意义(均P<0.05);总有效率中医组79.41%、西医组51.43%,中医组高于西医组,差异有统计学意义(χ2=5.953,P<0.05);治疗后中医组和西医组比较,中医组关节休息痛得分(t=1.787)和四肢活动能力得分(t=2.793)高于西医组,差异有统计学意义(均P<0.05)。结论中医药二联疗法可以提高成人大骨节病的显效率和总有效率,对改善患者四肢运动能力和关节休息痛的治疗效果明显,具有推广价值。
Objective To observe the clinical curative effect of traditional Chinese medicine combined therapy on adult Kashin-Beck disease and to select the treatment method of high quality, low cost, good curative effect and small side effect. Methods Sixty-nine patients with adult Kashin-Beck disease diagnosed were randomly divided into two groups: 34 cases treated with Chinese medicine combined therapy and 35 cases treated with Western medicine. Patients in Chinese medicine combined therapy group received self-administered oral administration of drug preparation and iontophoresis. Western medicine group Oral chondroitin sulfate and vitamin E. Results Before and after treatment, the clinical curative effect of Western medicine group (t = 9.418) and TCM group (t = 7.662) was statistically significant (all P <0.05); the total effective rate was 79.41% in TCM group and 51.43% in Western medicine group, Western medicine group, the difference was statistically significant (χ2 = 5.953, P <0.05); after treatment, the TCM rest group had significantly higher resting joint pain score (t = 1.787) and limb mobility score (t = 2.793) Western medicine group, the difference was statistically significant (P <0.05). Conclusion Traditional Chinese medicine dual therapy can improve the effective rate and total effective rate of adult Kashin-Beck disease, and has the obvious curative effect on improving the patients ’extremities’ motor ability and joint rest pain, and has the promotion value.