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目的:观察香砂六君子汤合旋覆代赭汤联合甲地孕酮改善肿瘤化疗患者生活质量的作用。方法:64例接受化疗的晚期肿瘤患者,随机分成2组,对照组口服甲地孕酮片;治疗组在对照组的基础上加用香砂六君子汤合旋覆代赭汤治疗。2个周期化疗后观察2组患者胃肠道反应、食欲、体重、卡氏评分(KPS)评分方面情况。结果:经2个周期化疗后,治疗组在胃肠道反应、食欲、体重、KPS评分方面均有明显改善。与对照组比较,差异均有统计学意义(P<0.05);胃肠道反应率治疗组0级、Ⅲ-Ⅳ级低于对照组,2组比较,差异均有统计学意义(P<0.05)。结论:香砂六君子汤合旋覆代赭汤联合甲地孕酮可明显降低晚期肿瘤患者化疗后胃肠道反应、提高食欲,改善患者化疗期间及化疗后的生活质量。
Objective: To observe the effect of Xiangsha Liujunzi Decoction combined with Chuanxuetai Decoction and Megestrol in improving the quality of life of patients with tumor chemotherapy. Methods: Sixty-four patients with advanced cancer undergoing chemotherapy were randomly divided into two groups. The control group received megesterone tablets. The treatment group was treated with Xiangsha Liujunzi Decoction and Daihuo Decoction on the basis of the control group. Gastrointestinal reactions, appetite, body weight, Kappa score (KPS) score were observed in 2 groups after 2 cycles of chemotherapy. Results: After two cycles of chemotherapy, the treatment group showed a significant improvement in gastrointestinal reactions, appetite, body weight and KPS scores. Compared with the control group, the difference was statistically significant (P <0.05); gastrointestinal reaction rate in the treatment group 0, Ⅲ-Ⅳ level was lower than the control group, the two groups, the difference was statistically significant (P <0.05 ). Conclusion: Xiangsha Liujunzi Decoction combined with megestrol can significantly reduce gastrointestinal reactions in advanced cancer patients after chemotherapy, improve appetite and improve the quality of life of patients after chemotherapy and chemotherapy.