消化性溃疡的病因与发病机理迄今尚未完全阐明,但近年来,这方面的研究进展较快,对本病的认识正在逐步深入,对治疗也开辟了新的途径。本文就发病机理和治疗上的有关进展予以介绍。发病机理一、胃粘膜屏障和消化性溃疡胃粘膜屏障是指在胃粘膜表面层和粘膜细胞之间的一道生理性屏障,它包括粘液屏障和粘膜细胞屏障西个方面。粘液屏障是指在胃粘膜细胞上覆盖着的一层粘稠的胶冻样的粘液层,主要由胃腺的粘液细胞所分泌, The etiology and pathogenesis of peptic ulcer has not yet been fully elucidated, but in recent years, research in this area has progressed rapidly. The understanding of this disease is gradually deepened, and a new way of treatment has also been opened up. This article on the pathogenesis and treatment of the related progress to be introduced. Pathogenesis First, the gastric mucosal barrier and peptic ulcer Gastric mucosal barrier refers to a physiological barrier between the gastric mucosal surface layer and mucosal cells, which includes the mucous barrier and mucosal cell barrier West aspects. Mucus barrier refers to the gastric mucosal cells covered with a layer of viscous jelly-like mucus layer, mainly by the gastric gland mucus cells secreted,