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目的:探讨α-硫辛酸、丹红注射液联合前列地尔治疗糖尿病周围神经病变的临床效果。方法:选取我院自2010年1月至2013年1月收治的68例糖尿病周围神经病变患者进行分析研究,随机分为2组,每组34例,观察组患者采用α-硫辛酸、丹红注射液、前列地尔联合进行治疗,对照组患者采用常规治疗方法进行治疗,观察两组患者治疗效果。结果:观察组患者治疗后的临床症状改善情况明显优于治疗前(P<0.05);且观察组临床症状改善情况也明显优于对照组(P<0.05),具有统计学意义。另外,观察组患者治疗总有效率达到94.12%,观察组患者治疗效果明显优于对照组(P<0.05),具有统计学意义。结论:采用多种药物联合治疗糖尿病周围神经病变,能够有效改善患者临床症状,减轻患者痛苦,提高治疗效果,安全、有效,值得临床推广应用。
Objective: To investigate the clinical effect of α-lipoic acid and Danhong injection combined with alprostadil in the treatment of diabetic peripheral neuropathy. Methods: Sixty-eight patients with diabetic peripheral neuropathy admitted to our hospital from January 2010 to January 2013 were randomly divided into 2 groups (34 in each). The patients in the observation group were treated with α-lipoic acid, Danhong Injection, alprostadil combined treatment of patients in the control group were treated with conventional treatment methods to observe the treatment effect of two groups of patients. Results: The improvement of clinical symptoms after treatment in observation group was better than that before treatment (P <0.05). The improvement of clinical symptoms in observation group was also better than that in control group (P <0.05), which was statistically significant. In addition, the total effective rate of observation group patients reached 94.12%, the treatment group was significantly better than the control group (P <0.05), with statistical significance. Conclusion: The combination of multiple drugs in the treatment of diabetic peripheral neuropathy can effectively improve the clinical symptoms, reduce the patient’s pain and improve the treatment effect. It is safe and effective and worthy of clinical application.