论文部分内容阅读
急性肺栓塞(acute pulmonary embolism,APE)是指内外源性栓子阻塞肺动脉导致肺循环异常的病理综合征,是临床常见危急重症。肺动脉压增高、肺循环阻力增加和肺血流异常引起右心室充盈压明显增加,心指数显著下降而导致右心室功能不全。血流动力学不稳定的APE临床常规抗凝治疗的基础上行手术治疗、溶栓或介入治疗,因而,生物标记物对APE血流动力学不稳定患者病情预测已无明显意义[1]。但生物标
Acute pulmonary embolism (APE) is a pathological syndrome characterized by extrinsic embolic blockage of the pulmonary artery leading to abnormal pulmonary circulation. It is a common clinical critically ill condition. Pulmonary hypertension, increased pulmonary vascular resistance and abnormal pulmonary blood flow caused by right ventricular filling pressure significantly increased cardiac index decreased significantly resulting in right ventricular dysfunction. Hemodynamic instability of APE clinical routine anticoagulant therapy based on the surgical treatment, thrombolysis or interventional therapy, therefore, biomarkers APE hemodynamic instability in patients with prognosis has no significant significance [1]. But the biological standard