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胃食管返流(Gastroesophageal reflux,GER),是指由于全身或局部原因引起下食管括约肌(Lower esophageal sphincter LES)功能不全,胃内容物返流入食管的一种病理状态,可产生一系列临床症状和引起一些严重的并发症和后遗症。GER是婴幼儿顽固性呕吐和生长发育迟缓的重要原因之一,常见的并发症有返流性食管炎、食管狭窄、食管溃疡及由于出血所致的贫血。近年研究证明GER与婴幼儿时期反复发作的肺炎、哮喘和支气管炎,以及窒息和婴儿猝死综合征(SIDS)均有密切关系。发病机理在食管下端腔内有一长约2～4cm的高压带,位于食管穿越膈肌之处,此即所谓LES。正常情
Gastroesophageal reflux (GER) refers to a pathological condition in which the contents of the stomach reflux into the esophagus due to systemic or local causes of lower esophageal sphincter LES insufficiency, resulting in a series of clinical symptoms and Cause some serious complications and sequelae. GER is one of the important reasons for intractable vomiting and growth retardation in infants and young children. Common complications are reflux esophagitis, esophageal stenosis, esophageal ulcer and anemia caused by bleeding. Recent studies have shown that GER is closely related to recurrent pneumonia, asthma and bronchitis in infants and young children, as well as asphyxia and sudden infant death syndrome (SIDS). Pathogenesis in the lower end of the esophagus cavity has a length of about 2 ~ 4cm high pressure zone, located in the esophagus through the diaphragm at this so-called LES. Normal love