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本文作者在这个问题上连续发表了两篇文章。第一篇论述了T细胞竭尽对小白鼠抗杜氏利什曼原虫免疫力的影响。内脏利什曼病的病人,出现非特异性的血液球蛋白增多和肝脾肿大,但不出现迟发型超敏反应。患者虽产生特异性的抗体,却没有证据说明存在体液免疫作用。如不予治疗,病人往往死亡,但一旦病人痊愈,通常产生迟发型超敏反应及长期持续的免疫力。至于免疫的性质,仍不甚明瞭。为了确定实验所致的T淋巴组织竭尽是否抑制小白鼠对杜
The author of this issue published two consecutive articles. The first discusses the T cell depletion of mice against Leishmania donovani immunity. Visceral leishmaniasis patients, non-specific increase in hemoglobin and hepatosplenomegaly, but does not appear delayed type hypersensitivity. Although patients produce specific antibodies, there is no evidence that there is humoral immunity. Without treatment, patients often die, but often have delayed-type hypersensitivity and long-lasting immunity once the patient has healed. As for the nature of immunity, it is not clear. In order to determine whether the experimental T lymphoid tissue do all to suppress the mouse Du