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目的评价深部聚焦热疗联合三维适形放疗治疗晚期非小细胞肺癌(NSCLC)的近期临床疗效。方法晚期NSCLC患者69例,其中联合组30例,单放组39例,放疗采用三维适形放疗,热疗采用深部聚焦热疗,每次均于放疗结束后2h内进行。结果联合组CR 10例,PR 15例;单放组CR 8例,PR 16例,两组局部有效率分别为83.3%和61.5%(P<0.05);联合组的不良反应较单放组未增加。结论放疗联合热疗较单纯放疗可以提高晚期NSCLC的局部有效率,降低放射反应,提高生活质量。
Objective To evaluate the clinical efficacy of deep focused hyperthermia combined with three-dimensional conformal radiotherapy for advanced non-small cell lung cancer (NSCLC). Methods 69 cases of advanced NSCLC patients, including 30 cases of combined group, 39 cases of radiotherapy group, radiotherapy using three-dimensional conformal radiotherapy, hyperthermia using deep focusing hyperthermia, each time within 2h after the end of radiotherapy. Results There were 10 CRs and 15 PRs in the combination group, 8 CRs in the radiotherapy group and 16 PRs in the combination group. The local effective rates were 83.3% and 61.5%, respectively (P<0.05). The adverse reactions in the combination group were lower than those in the radiotherapy group. increase. Conclusion Compared with radiotherapy alone, radiotherapy combined with hyperthermia can improve the local efficiency of advanced NSCLC, reduce radiation response and improve quality of life.