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氯丙嗪是吩噻嗪类中的一种重要衍生物,是镇静作用强的一种抗精神病药物。1950年生产以来,开始用于镇吐、催眠等。1952年开始应用于治疗精神病获得较好的效果。30年来临床实践证实是治疗精神病有效的药物,一般是治疗精神分裂症的首选药物。药理作用:各国学者从电生理学、条件反射和生物学等方面进行研究,发现氯丙嗪的药理作用很复杂,涉及中枢神经系统及植物神经系统、内分泌,代谢等各方面,但目前各学者的意见尚未完全统一。它具有抗精神病、降压、降温和降低基础代谢、抗肾上腺素、抗组织胺、镇吐、加强麻醉剂和催眠剂等作用。在觉醒状态下可保持情绪稳定。
Chlorpromazine is an important derivative of phenothiazines, is a sedative anti-psychotic drugs. Since production in 1950, began to use for vomiting, hypnosis and so on. 1952 began to apply to the treatment of psychiatric patients get better results. 30 years of clinical practice has proven to be effective in the treatment of psychiatric drugs, generally the treatment of schizophrenia drug of choice. Pharmacological effects: Scholars from all walks of life from electrophysiology, conditioned reflect and biological aspects of the study found that the pharmacological effects of chlorpromazine is very complex, involving the central nervous system and autonomic nervous system, endocrine, metabolism and other aspects, but the current scholars Opinion has not yet been completely unified. It has antipsychotic, antihypertensive, antihypertensive and reduce the basal metabolism, anti-epinephrine, antihistamine, antiemetic, strengthening anesthetic and hypnotic agents and so on. In arousal to maintain emotional stability.