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肝硬化患者有多种凝血因子减少,部分病人有纤维蛋白溶酶活性增加。并有脾功能亢进的患者行脾脏切除术是外科治疗的有效措施之一。但少数病人在术中和/或术后的24小时内有渗血难止现象,个别病人在术后伴发深部静脉血栓。有作者认为脾脏是与生理性抗凝系统有关的器官。因此,探索脾功能亢进患者切脾前后的凝血机制改变有其实际意义。
Patients with cirrhosis have a variety of coagulation factors decreased, some patients have increased plasmin activity. One of the effective measures of surgical treatment is splenectomy in patients with hypersplenism. However, a small number of patients in the intraoperative and / or postoperative 24 hours bleeding difficult to stop the phenomenon, some patients with postoperative deep venous thrombosis. According to the author, the spleen is an organ related to the physiological anticoagulation system. Therefore, to explore the spleen hyperthyroidism before and after splenectomy coagulation mechanism has its practical significance.