药物洗脱支架的出现是冠脉疾病介入治疗的第三大里程碑,它明显地降低了支架内再狭窄率和靶病变重建率,然而因内皮化不全导致的支架血栓并发症对患者往往是致命的打击,也是目前亟待解决的主要临床问题。该文简要介绍药物洗脱支架血栓的发生、发展、主要机制及相关的防治措施进展。 The emergence of drug-eluting stents is the third milestone in the interventional treatment of coronary artery disease, which significantly reduces the rate of in-stent restenosis and target lesion reconstruction rates, however, stent thrombosis complications due to endothelium degeneration are often fatal to patients It is also the main clinical problem to be solved urgently. This article briefly introduces the occurrence and development of drug-eluting stent thrombosis, the main mechanisms and the progress of prevention and treatment measures.