老年人由于各种器官代谢功能减退,清除、中和药物毒性的防御能力下降,对药物耐受能力降低。滥用或用药不当可损伤机体的组织,干扰或破坏器官的正常功能,造成严重的不良反应甚至药源性疾病。轻则延长原疾病的病程,重则导致终身残疾甚至危及生命,因此,老年人用药更需十分重。 Elderly due to a variety of organ metabolism decreased, clearance, neutralization and drug toxicity decreased defensive ability to reduce drug tolerance. Misuse or improper medication can damage the body’s tissues, interfere with or destroy the normal function of organs, causing serious adverse reactions and even drug-induced diseases. Ranging from prolonging the course of the original disease, leading to life-long disabilities or even life-threatening, therefore, the elderly need more serious medication.