患者男性,56岁,白人。1982年1月发生心肌梗塞,当时其血红蛋白为15.1g/dl,白细胞6600/μl,多形核白细胞75％。开始用普鲁卡因酰胺每天750mg以治疗心室异位心律,其他仅用异山梨醇二硝酸盐,由于持续性心绞痛,预定做选择性心导管检查,于1982年3月12日住院,此时其白细胞为1500/μl,多形核白细胞4％,淋巴细胞80％,单核细胞16％,血红蛋白13.6g/dl,血小板247,000/μl,骨髓穿刺检查示早幼粒细胞阶殴后的骨髓细咆成份缺乏,淋巴细胞相对增多达33％,红系呈巨幼样特征。抗核抗体1:20阳性,提示药物引起的红斑狼疮综合征。于是停用昔鲁卡因酰胺,10天后患者有低热和肌痛,用抗生素治疗,但没有感染的证据。其骨髓恢复先表现为一过性单核细 Male patient, 56 years old, white. Myocardial infarction occurred in January 1982 when hemoglobin was 15.1 g / dl, white blood cells 6600 / μl, and polymorphonuclear leukocytes 75%. 750 mg of procainamide was started daily for the treatment of ventricular ectopic heart rhythms and the other only for isosorbide dinitrate. Due to persistent angina, a scheduled cardiac catheterization was scheduled for hospitalization on March 12, 1982, when The white blood cells were 1500 / μl, polymorphonuclear leukocytes 4%, lymphocytes 80%, monocytes 16%, hemoglobin 13.6g / dl, platelets 247,000 / μl, bone marrow aspirate showed promyelocytosis after bone marrow fine Roaring lack of ingredients, relative increase in lymphocytes up to 33%, red line was giant juvenile features. Anti-nuclear antibodies 1:20 positive, suggesting that drug-induced lupus syndrome. As a result, delavirdine was discontinued and, after 10 days, patients had hypothermia and myalgia treated with antibiotics but no evidence of infection. The bone marrow recovery first showed a transient mononuclear