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目的:探讨贵阳地区老年心脑血管疾病的危险因素。方法:随机抽取贵阳地区1 865例老年人(≥60岁)作为研究对象,分为心脑血管疾病组及非心脑血管疾病组,并比较2组人群性别、年龄、体重指数(BMI)、腰臀比(WHR)、收缩压(SBP)、舒张压(DBP)、脉压(PP)、空腹血糖(FPG)、餐后2 h血糖(2h PG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)、甘油三酯(TG)、血肌酐(Scr)、糖化血红蛋白(Hb A1c)、踝臂指数(ABI)、吸烟、运动等指标;以心脑血管疾病为因变量,上述指标为自变量进行Logistic回归分析心脑血管疾病的独立影响因素。结果:心脑血管疾病组ABI异常率高于非心脑血管疾病组,ABI均值低于非心脑血管疾病组(P<0.05);心脑血管疾病组的年龄、SBP、PP、FPG、2h PG、SCr、Hb A1c的水平及高血压、血脂异常症、糖尿病的比例均高于非心脑血管疾病组,运动的比例低于非心脑血管疾病组(P<0.05),其余指标比较,差异无统计学意义(P>0.05);Logistic回归分析结果显示,年龄(OR=1.135,P<0.01)、运动(OR=0.524,P<0.05)、高血压(OR=2.001,P<0.01)、血脂异常症(OR=2.201,P<0.01)和ABI异常(OR=3.560,P<0.01)是老年心脑血管疾病的独立影响因素。结论:ABI降低使贵阳地区的老年患者发生心脑血管疾病的风险增加,ABI、年龄、高血压、血脂异常症、运动是贵阳地区老年心脑血管疾病的独立影响因素。
Objective: To explore the risk factors of cardiovascular and cerebrovascular diseases in the elderly in Guiyang. Methods: A total of 1 865 elderly (≥60 years old) in Guiyang were randomly divided into cardiovascular and non-cardiovascular disease groups. Gender, age, body mass index (BMI) WHR, SBP, DBP, PP, FPG, 2h PG, HDL-C, LDL-C, TC, TG, Scr, Hb A1c, ABI, smoking, exercise and so on Indicators; cardiovascular and cerebrovascular disease as the dependent variable, the above indicators as independent variables Logistic regression analysis of cardiovascular and cerebrovascular disease independent factors. Results: The abnormal rate of ABI in cardiovascular and cerebrovascular disease group was higher than that in non-cardiovascular and cerebrovascular disease group, mean ABI was lower than that in non-cardiovascular and cerebrovascular disease group (P <0.05), and age, SBP, PP and FPG The levels of PG, SCr and Hb A1c and the proportion of hypertension, dyslipidemia and diabetes were higher in non-cardiovascular and cerebrovascular diseases than those in non-cardiovascular and cerebrovascular diseases (P <0.05) Logistic regression analysis showed that age (OR = 1.135, P <0.01), exercise (OR = 0.524, P <0.05), hypertension (OR = 2.001, P <0.01) , Dyslipidemia (OR = 2.201, P <0.01) and abnormal ABI (OR = 3.560, P <0.01) were the independent influencing factors of cardiovascular and cerebrovascular diseases in the elderly. CONCLUSION: ABI decreased the risk of cardiovascular and cerebrovascular diseases in elderly patients in Guiyang. ABI, age, hypertension, dyslipidemia and exercise are the independent influencing factors of cardiovascular and cerebrovascular diseases in Guiyang.