论文部分内容阅读
目的 提高血管扩张性骨肉瘤的早期诊断水平 ,避免误诊或延误治疗。 方法 对1991～ 1998年收治的 10例血管扩张性骨肉瘤患者的临床影像病理特征进行回顾总结。 10例患者中 ,男 6例 ,女 4例 ,平均年龄 2 3.4岁。病灶部位 :骨干 5例 ,其中股骨干 2例 ,肱骨干 3例 ;干骺端偏干侧3例 ,其中股骨上段 1例 ,胫骨上段 2例 ;骨端 2例 ,其中股骨下端 1例 ,胫骨下端 1例。术前仅 2例经切开活检诊断为血管扩张性骨肉瘤 ;术前化疗 8例 ,行保肢手术 3例 ,截肢 7例。 10例患者均行术后化疗。 结果 经 6～ 72个月 (平均 2 8个月 )随访 ,6例肺转移 ,5例死亡 ,1例带瘤存活 ,余 4例无瘤存活 ,均未出现局部复发。 结论 对血管扩张性骨肉瘤应结合临床影像病理 ,早期明确诊断并施以正确治疗。
Objective To improve the early diagnosis of vasodilator osteosarcoma and avoid misdiagnosis or delayed treatment. Methods The clinical imaging and pathological features of 10 patients with vasodilator osteosarcoma admitted from 1991 to 1998 were retrospectively reviewed. Of the 10 patients, 6 were males and 4 were females with an average age of 23.4 years. Lesions: 5 cases of the backbone, including 2 cases of femoral shaft and 3 cases of humeral shaft; 3 cases of metaphyseal side, including 1 case of upper femur and 2 cases of upper humerus; 2 cases of bone end, including 1 case of lower femur Lower case. Only 2 patients who underwent open biopsy were diagnosed as vasodilator osteosarcoma before surgery. 8 patients received preoperative chemotherapy, 3 patients underwent limb salvage surgery, and 7 patients underwent amputation. All 10 patients received postoperative chemotherapy. Results After 6-72 months (average 28 months) follow-up, 6 cases of lung metastasis, 5 cases of death, 1 case with tumor survival, and the remaining 4 cases survived without tumor, and no local recurrence. Conclusion The vasodilator osteosarcoma should be combined with clinical imaging pathology, early diagnosis and correct treatment.