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人类T细胞白血病病毒(HTLV-1)是从人类T细胞肿瘤中分离出来的逆转录病毒,对人类T辅助细胞(T_H)有强大的亲和力,这种病毒可由作为T_H 细胞瘤的成人T细胞白血病(ATL)中重新分离出来,所以,它是瞩目的ATL病原。在ATL多发区人群中,有不少HTLV-1抗体阳性的带毒者,说明HTLV-1感染蔓延较广泛。大部分带毒者不发病.极少数感染者经长期潜伏后发病。以前,作者等对人类白血病与淋巴瘤进行病毒学检查时,发现有逆转录病毒与疱疹病毒双重感染,以后培养成功能连续复制HTLV-1和EB病毒的克隆
Human T-cell leukemia virus (HTLV-1), a retrovirus isolated from human T-cell tumors, has a strong affinity for human T-helper cells (T_H), which is recognized by T-H cell tumors as adult T-cell leukemia (ATL), so it is the ATL cause of concern. In ATL-prone population, there are many HTLV-1 antibody-positive carriers, indicating that HTLV-1 infection is more widespread. Most infected persons do not have any disease, and very few are affected by long-term latent disease. Previously, the author of virological tests of human leukemia and lymphoma found double infection with retrovirus and herpes virus, and later successfully cultured HTLV-1 and EB virus clone