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随着药物品种的与日俱增和临床需要,合并用药在治疗中越来越多地被采用.合并用药必然要引起药物之间的相互作用,药物相互作用可使作用增强或减弱,作用的持久性亦可延长或缩短,相互作用的后果可以表现为有益的治疗作用或有害的不良反应。目前有些病(心血管、肿瘤、结核等)趋向联合用药治疗,这样虽有多方面的优点,但毕竞增加了药物相互作用后不良反应发生的机会.常见的相互作用可概括为三大类:理化的相互作用;药动学的相互作用;药效学的相互
With the growing variety of drugs and clinical needs, the combination of medication is increasingly being used in the treatment.Mixed drugs inevitably lead to the interaction between drugs, drug interactions can enhance the role of or weakened, the role of persistence can Prolonged or shortened, the consequences of an interaction may manifest as a beneficial therapeutic effect or a detrimental adverse effect. At present, some diseases (cardiovascular, oncological, tuberculosis, etc.) tend to be treated with combination therapy, though there are many advantages, Bi Bi has increased the chances of adverse reactions after drug interactions.Common interactions can be summarized into three categories : Physicochemical interactions; Pharmacokinetic interactions; Pharmacodynamic interactions