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目的分析近几年宝鸡市中医医院高血压药物的临床应用情况,对合理性进行分析。方法随机选择该院2009-2011年1 860份高血压患者的处方进行统计分析,观察抗高血压药物的常用种类及使用情况。结果临床使用最多的是钙离子拮抗剂,其排列顺位是钙离子拮抗剂(CCB)44.14%、β-受体阻滞剂21.4%、ACEI17.26%、ARB6.67%、利尿剂5.49%和复方制剂4.95%。CCB使用率明显高于其它药物(P<0.05)。使用率最高的两种药物是硝苯地平控释片和氨氯地平片,使用率大大高于其它降压药(P<0.05)。1 860份处方中共发现23份,占1.26%,分别为重复用药18份,剂量偏大2份,用药不合理1份,剂量偏小2份。结论高血压用药应根据指南要求个体化联合用药,总体来看,该院高血压用药基本合理,但还应加强临床用药指导,降低不合理用药。
Objective To analyze the clinical application of hypertension drugs in Baoji TCM Hospital in recent years and analyze its rationality. Methods A total of 1860 hypertensive patients in our hospital from 2009 to 2011 were randomly selected and statistically analyzed. The common types and usage of antihypertensive drugs were observed. Results The most commonly used calcium antagonists were cisplatin with 44.14% of calcium channel blockers, 21.4% of β-blockers, 17.26% of ACEIs, 6.67% of ARBs and 5.49% of diuretics. And compound preparation 4.95%. CCB usage was significantly higher than other drugs (P <0.05). The two drugs with the highest rates of use were nifedipine and amlodipine, with significantly higher rates of use than other antihypertensives (P <0.05). A total of 1 860 prescriptions were found in 23, accounting for 1.26%, were repeated medication 18, 2 doses were too large, irrational medication 1, 2 doses. Conclusion Hypertension medication should be based on the guidelines required individualized combination therapy, on the whole, the hospital hypertension medication is reasonable, but should also strengthen the guidance of clinical medication, reduce irrational medication.