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短期研究发现,睾酮替代治疗能预防男性受试者运动中心肌缺血和改变心血管危险因素,例如胰岛素抵抗力,脂肪含量,脂类。Mathur A等进行了一项随机、安慰剂、平行对照实验,观察了睾酮替代治疗12个月后,对低睾酮水平伴心绞痛男性患者运动引起的心肌缺血、脂类、颈动脉内膜中层厚度(CIMT)和身体成分等的影响。结果:15人入选,但只有13人完成了全程随访。7人予以睾酮治疗,6人予以安慰剂治疗。睾酮延长了运动开始到出现心肌缺血的时间[(129±8)s Vs(12±18)s,P=0.02]和血红素含量[(0.4±0.6)g/dl Vs
Short-term studies have found that testosterone replacement therapy prevents myocardial ischemia and changes in cardiovascular risk factors such as insulin resistance, fat content, and lipids in exercise-induced events in male subjects. In a randomized, placebo-controlled, parallel-controlled trial, Mathur A et al. Observed the effects of exercise-induced myocardial ischemia, lipids, carotid artery intima-media thickness in men with low testosterone and angina pectoris after 12 months of testosterone replacement therapy (CIMT) and body composition and so on. Results: Fifteen were selected, but only 13 completed the full follow-up. Seven were given testosterone and six were given placebo. Testosterone prolonged the duration of onset of myocardial ischemia [(129 ± 8) s Vs (12 ± 18) s, P = 0.02] and heme level [(0.4 ± 0.6) g / dl Vs